Approved Tesa 10

Tesamorelin is a synthetic Growth Hormone–Releasing Hormone (GHRH) analog, designed to stimulate the natural release of growth hormone (GH) from the pituitary gland. By extending the half-life of native GHRH through amino acid substitutions, Tesamorelin provides a longer-lasting and more potent stimulation of GH secretion.

Initially developed for the treatment of HIV-associated lipodystrophy, Tesamorelin has since become a peptide of significant research interest in body composition, fat metabolism, and healthy aging.

Research Applications and Benefits

Tesamorelin’s activity centers on its ability to elevate endogenous growth hormone and downstream IGF-1, with research applications that include:

• Visceral Fat Reduction
  Clinical studies demonstrated Tesamorelin’s ability to reduce visceral adipose tissue (VAT) — a dangerous fat depot linked to metabolic and cardiovascular disease.

• Metabolic Health
  By decreasing VAT and improving lipid profiles, Tesamorelin has been studied for its ability to improve insulin sensitivity and reduce cardiometabolic risk factors.

• Muscle Preservation and Performance
  Through GH/IGF-1 elevation, Tesamorelin supports muscle anabolism, recovery, and performance optimization in research models.

• Healthy Aging and Longevity
  As growth hormone secretion naturally declines with age, Tesamorelin has been investigated for its potential to restore youthful GH rhythms and mitigate aspects of age-related decline.

• Neurocognitive Research
  Early studies suggest Tesamorelin may improve cognitive function and memory, linking GH/IGF-1 pathways to brain health.

As with all peptides offered for research purposes only, Tesamorelin is not intended for human consumption unless prescribed in approved settings. 

• Stability – Supplied in lyophilized form, requiring storage in a cool, dry environment until reconstitution.
• Regulatory Status – Tesamorelin is FDA-approved under a specific brand for the treatment of HIV-related lipodystrophy, but all other uses remain investigational. Research-grade Tesamorelin is not approved as a general therapy or supplement.
• Research Integrity – Laboratory studies should be conducted under strict regulatory compliance and ethical oversight.

Tesamorelin is a potent GHRH analog that has demonstrated clinical efficacy in reducing visceral fat and improving metabolic health, while also offering insights into muscle preservation, cognitive function, and longevity research.

For researchers exploring the intersections of growth hormone biology, metabolism, and aging, Tesamorelin represents one of the most clinically validated and scientifically compelling peptides available today.