Approved IPA 5

Ipamorelin is a synthetic pentapeptide and one of the most selective Growth Hormone Secretagogues (GHSs) developed to date. As a ghrelin receptor (GHS-R1a) agonist, Ipamorelin mimics the action of ghrelin to stimulate the pituitary gland to release growth hormone (GH).

Unlike earlier GHS compounds (such as GHRP-6 or GHRP-2), Ipamorelin is distinguished by its clean pharmacological profile. It strongly promotes GH release while minimizing side effects such as cortisol or prolactin elevation, making it a leading research tool in the study of growth, metabolism, and recovery.

Research Applications and Benefits

Ipamorelin has been studied in both preclinical and clinical settings, with findings that highlight several potential applications:

Growth Hormone Stimulation
Ipamorelin selectively increases GH release, supporting research into anabolism, tissue repair, and recovery.

Muscle Growth and Recovery
By raising GH levels, Ipamorelin may accelerate muscle regeneration, strength adaptation, and post-injury healing in experimental models.

Fat Metabolism
Growth hormone plays a central role in lipolysis. Ipamorelin’s ability to raise GH without unwanted hormonal effects makes it a valuable compound in fat metabolism studies.

Bone and Connective Tissue Support
Research suggests GH secretagogues like Ipamorelin may positively influence bone density and tendon/ligament health, making them relevant in orthopedic and regenerative studies.

Synergy with Other GHRH Analogs
Ipamorelin is often studied alongside CJC-1295 or Sermorelin, where the combination enhances pulsatile GH release in a physiologically consistent manner.

As with all peptides available for research purposes only, Ipamorelin is not approved for human consumption or therapeutic use. 

• Stability – Provided in lyophilized form, Ipamorelin should be stored in a cool, dry environment until reconstituted.
• Regulatory Status – Ipamorelin remains investigational and is not FDA-approved.
• Research Integrity – Studies should remain confined to controlled laboratory environments with full compliance to ethical and regulatory standards.

Ipamorelin is one of the most selective and well-tolerated growth hormone secretagogues, offering researchers a precise tool to study the role of GH in muscle repair, fat metabolism, recovery, and healthy aging.

Its favorable safety profile compared to earlier secretagogues makes Ipamorelin a cornerstone peptide in research on the GH/IGF-1 axis and regenerative medicine.