GLOW (GHK-Cu) – Research Peptide Review

Origins in Skin Regeneration

The peptide commonly referred to as GLOW is the copper-binding tripeptide GHK-Cu (Gly-His-Lys-Cu), originally identified in the 1970s in human plasma. Researchers discovered its remarkable ability to stimulate wound healing, tissue remodeling, and skin regeneration. Since then, GHK-Cu has become one of the most studied cosmetic and regenerative peptides, earning the nickname “the glow peptide” for its ability to promote youthful, vibrant skin appearance in research and topical formulations.

Research Applications and Benefits

GHK-Cu has been widely investigated in dermatological, cosmetic, and regenerative research with findings that support a variety of benefits:

• Skin Regeneration and Anti-Aging
  Studies show GHK-Cu may stimulate collagen and elastin production, helping restore firmness and elasticity to the skin.

• Wound Healing
  As a natural signal peptide, GHK-Cu plays a role in cell migration and angiogenesis, supporting faster and more efficient tissue repair.

• Hair Growth
  Research suggests GHK-Cu may stimulate hair follicle activity and extend the anagen (growth) phase of hair cycles.

• Antioxidant and Anti-Inflammatory Effects
  By modulating gene expression, GHK-Cu appears to reduce oxidative stress and inflammatory responses at the tissue level.

• Skin Tone and Texture
  Laboratory and cosmetic studies highlight GHK-Cu’s ability to improve skin clarity, smoothness, and pigmentation balance, contributing to its reputation as a “cosmetic rejuvenator.”

As with all peptides provided for research purposes only, GHK-Cu is not approved for human use, supplementation, or medical treatment.

• Formulation Stability – Often supplied in lyophilized form for stability. In topical research, it is studied for its ability to penetrate the skin barrier when formulated with proper carriers.
• Regulatory Status – GHK-Cu remains investigational as a peptide. While it is included in some cosmetic preparations, it is not FDA-approved for therapeutic claims.
• Research-Only Application – GHK-Cu should be used strictly for laboratory research in compliance with ethical and regulatory standards.

GLOW (GHK-Cu) represents one of the most promising peptides in cosmetic and regenerative research, with decades of studies supporting its ability to rejuvenate skin, support wound healing, reduce inflammation, and restore youthful tissue architecture.

Its reputation as the “peptide of renewal” continues to grow, making it a key research tool in understanding the intersection of aesthetics, healing, and molecular regeneration.