Approved AOD 5

AOD-9604 is a synthetic fragment of the human growth hormone (HGH) molecule, specifically amino acids 176–191. Developed in the 1990s by Australian researchers, it was designed to retain the fat-metabolizing properties of HGH without its unwanted anabolic or growth-related effects.

Unlike full-length HGH, which acts on multiple pathways, AOD-9604 appears to selectively influence lipolysis (fat breakdown) and anti-lipogenesis (prevention of fat formation). This unique selectivity has made it a leading research peptide for investigating obesity, metabolism, and weight management.

Research Applications and Benefits

Preclinical and human studies have highlighted several potential applications for AOD-9604:

• Fat Metabolism
  AOD-9604 enhances the breakdown of stored fat and prevents the accumulation of new fat cells, making it a strong candidate for obesity and weight regulation studies.

• Glucose Tolerance and Metabolic Health
  Research suggests AOD-9604 may improve insulin sensitivity and glucose tolerance, positioning it as a compound of interest in metabolic syndrome research.

• Joint and Cartilage Support
  Some evidence indicates AOD-9604 may promote cartilage regeneration and reduce joint inflammation, expanding its relevance beyond fat metabolism.

• Non-Anabolic Profile
  Unlike growth hormone, AOD-9604 does not stimulate IGF-1 or tissue overgrowth, making it potentially safer for long-term research in metabolism-focused studies.

• Obesity-Related Disorders
  Animal and early human studies point toward beneficial effects in reducing visceral fat, a major risk factor for cardiovascular and metabolic diseases.

Special Considerations

As with all peptides offered for research purposes only, AOD-9604 is not approved for human use, supplementation, or therapeutic application. 

• Stability – Typically supplied in lyophilized form, requiring storage in a cool, dry environment until reconstitution.
• Regulatory Status – While AOD-9604 has undergone clinical testing and has been reviewed as a potential therapeutic, it remains unapproved by the FDA and is investigational worldwide.
• Research Integrity – Research should remain within controlled laboratory environments and follow all ethical and regulatory guidelines.

AOD-9604 represents a targeted derivative of human growth hormone, designed to isolate its fat-burning and metabolic effects without unwanted anabolic activity. With applications in obesity research, glucose regulation, and joint health, AOD-9604 provides researchers a unique tool to study the pathways that influence body composition and metabolic resilience.

For scientists exploring the frontiers of fat metabolism and weight management, AOD-9604 is an invaluable peptide for advancing the understanding of energy balance and metabolic health.